More Than Sick of Salt

Dr. DePace’s Books

We are a private cardiovascular practice. We are not owned or leased by any hospital system or healthcare system. Our primary interest is in our patients and their care.

Therefore, the diagnoses and options we provide for our patients are based on providing them the most optimal treatment and in accordance with their preferences.

Many physicians treat patients with excellence but few write books and publish peer review articles while also treating patients excellently.

 

WE WRITE THE BOOKS AND PAPERS!

 

 

 

 

 

 

 

 

 

 

 

 

 

Ehlers-Danlos/Hypermobility Syndromes and Other Connective Tissue Disorders: Assessments, Diagnostics, and Therapies

 

 

 

 

 

 

 

 

Book Summary

This book covers Ehlers-Danlos and hypermobility syndromes with an emphasis on treatment of the parasympathetic and sympathetic (P&S) nervous system dysfunctions. Unfortunately, most EDS/HSD patients have been misdiagnosed and misunderstood by providers. EDS/HSD is a multisystem, multifaceted disorder that is poorly understood. The P&S manifestations and treatments are also poorly understood throughout the healthcare community. To this end the authors wish to teach providers and patients alike to reduce the life-long suffering from both the disorder and the marginalization.

There are two aspects of teaching that are required and provided by this book: improved understanding of EDS/HSD and improved understanding of P&S (autonomic) dysfunction and treatment. For example, with the autonomic nervous system, more treatment or therapy is never better. Relief of P&S dysfunction must be low and slow to prevent causing more symptoms from higher doses of medication or polypharmacy. To this end, stress often sets patients back and both providers and patients alike must have proper expectations set for successfully improving patient outcomes (quality of life and productivity).

The book starts with an introduction to and history of the disorder. Chapter II provides a review of the genetics of collagen, the source of the disorders. Chapters III through IX detail the various forms of EDS/HSD and goes into more detail on the more common and more well-known variants of EDS/HSD. Chapter X discusses structural cardiovascular and pulmonary dysfunction associated with EDS/HSD. Chapter XI discusses structural gastrointestinal and urogenital dysfunction associated with EDS/HSD. The book ends with Chapter XII, which details the involvement of the P&S nervous systems and how to treat, which also has general application to other chronic disorders.

This is an ideal guide for rheumatologists and primary care physicians treating patients with Ehlers-Danlos and hypermobility syndromes, and patients and their loved ones in understanding their disease and disorders and the associated treatments and therapies.

This book was published on September 27, 2025. Click here or the image to order

 

Anxiety and Dysautonomia: Do I Have POTS or Autonomic Dysfunction?

 

 

 

 

 

 

 

 

This book was published on September 26, 2023. Click here or the image to order

Book Summary

What causes anxiety to be so prevalent in so many people? How is it best prevented and treated? What can patients and physicians do to better understand this common medical issue?

Anxiety is a component of many physical and mental disorders, from depression to PTSD. Unfortunately, not many patients find relief in the associated therapies and medications, and simply adding more of the same often causes other disorders. Additionally, many who suffer from anxiety may in fact have other, anxiety-like conditions, such as the frequently misdiagnosed postural orthostatic tachycardia syndrome (POTS), which can make any attempt at treatment futile.

But now, with Anxiety and Dysautonomia: Do I Have POTS or Autonomic Dysfunction, Donald J. Parker and physicians Joseph Colombo and Nicholas L. DePace aim to show, with a simplified analysis and discussion focusing on this common patient complaint and how best to treat it, that no longer does anxiety need to be merely managed with the forced lifestyle changes that are often required. Topics covered include: ​

  • Parasympathetic and Sympathetic (P&S) dysfunctions that lead to anxiety-like conditions, plus clear concepts of anxiety and anxiety-like symptoms, the six-pronged Mind-Body Wellness Program, and the P&S nervous systems.
  • How many of these anxiety-like conditions are actually caused by a lack of proper blood flow to the brain, which may cause mild symptoms of depression, fatigue, malaise, brain fog, and cognitive and memory difficulties, sleep difficulties and more.
  • The way these issues, when exacerbated, may trigger “adrenaline storms” that cycle the anxiety-like symptoms.
  • Treatments that in many cases enable a return to a “normal” (as defined by the patient) quality of life, including natural therapies to relieve symptoms and promote wellness.

Presenting discussions with patients and doctors side-by-side to help physicians see how to present information to their patients and patients to learn what physicians need to know to tailor therapy to their individual needs, Anxiety and Dysautonomia is an essential resource for anyone concerned with anxiety and anxiety-like disorders, from medical professionals to patients to family and friends.

 

Fatigue and Dysautonomia: Chronic or Persistent, What’s the Difference?

 

 

 

 

 

 

 

 

This book was published on September 26, 2023. Click here or the image to order

Book Summary

What causes chronic and persistent fatigue in so many people? How is it best prevented and treated? What can patients and physicians do to better understand this common medical issue?

Fatigue is an extremely common component of many physical and mental disorders, from anxiety and depression to heart disease and hypertension. Many patients even find themselves suffering from persistent fatigue with little understanding of how to safely and effectively treat the issue, especially if their symptoms don’t qualify for diagnosis as Chronic Fatigue Syndrome, which can make them “fall through the cracks” of the medical system.

But now, with Fatigue and Dysautonomia: Chronic or Persistent, What’s the Difference?, physicians Joseph Colombo and Nicholas L. DePace aim to close those cracks, offering a simplified analysis and discussion focusing on this common patient complaint and how best to treat it. Topics covered include: ​

  • Parasympathetic and Sympathetic (P&S) causes of both Chronic and “Persistent” Fatigue
  • Natural therapies to help relieve Fatigue and promote wellness.
  • Concepts of Fatigue, the six-pronged Mind-Body Wellness Program, and the P&S nervous systems.
  • Causal relationships between Fatigue and P&S dysfunction (a more specific description of autonomic dysfunction or dysautonomia)
  • How to treat fatigue with supplements and lifestyle modifications that have been documented to work without the added side-effects of most pharmaceutical therapies.

Presenting discussions with patients and doctors side-by-side to help physicians see how to present information to their patients and patients to learn what physicians need to know to tailor therapy to their individual needs, Fatigue and Dysautonomia is an essential resource for anyone concerned with fatigue, from medical professionals to patients to family and friends.

 

Clinical Autonomic Dysfunction and Mitochondrial Disorders, DePace N.L., Colombo J. Springer Publishers 2019, New York. This text deals with treatment of autonomic dysfunction disorders.

 

 

 

 

 

 

 

 

 

This book was published on August 24, 2019. Click here or the image to order

 

Clinical Autonomic Dysfunction. Colombo J. Aurora, DePace, Vinnik, Springer Publishers New York, 2014. This book deals with assessment and testing of autonomic function and identifying autonomic dysfunction disorders.

 

 

 

 

 

 

 

 

This book was published on October 7, 2014. Click here or the image to order

 

The Heart Repair Manual. The Philadelphia Formula for Reversing Heart Disease. W.W. Norton New York, New York, 1992, DePace, N.L., Dowinsky, S. This book predated the Framingham Risk Score. It stratifies cardiac patients in to risks quantitatively and offers a program and measures to treat, stabilize and possibly reverse atherosclerotic heart rate disease.